Sequence 1018(mcPLA2)

Sequence mcPLA2
Target	Pla2g4a ( Mus musculus )
Description	Phospholipase A2, group IVA ( cytosolic, calcium-dependent ) Ensembl: ENSMUSG00000056220 UniGene: Mm.4186 EntrezGene: 18783
Design	siRNA
Chemistry	RNA
Sequence	siRNA sense (21b) ACCCTAGGCACAGCTACATTT / siRNA antisense (21b) ATGTAGCTGTGCCTAGGGTTT
Application	gene silencing
Name	mcPLA2

References

Ceramide 1-phosphate is a direct activator of cytosolic phospholipase A2.Pettus BJ, Bielawska A, Subramanian P, Wijesinghe DS, Maceyka M, Leslie CC, Evans JH, Freiberg J, Roddy P, Hannun YA, Chalfant CE.J Biol Chem. 2004 Mar 19;279(12) :11320-6. Epub 2003 Dec 15.

Intrathecal Injections in Children With Spinal Muscular Atrophy: Nusinersen Clinical Trial Experience. Hache M, Swoboda KJ, Sethna N, Farrow-Gillespie A, Khandji A, Xia S, Bishop KM. J Child Neurol. 2016 Jun;31(7):899-906. PubMed:26823478

Background