Sequence 1063(RasGRP1-RNAi1419 , RasGRP1RNAi1419)

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Sequence RasGRP1-RNAi1419 , RasGRP1RNAi1419
Target RASGRP1 ( Homo sapiens )
Description RAS guanyl releasing protein 1 ( calcium and DAG-regulated )

Ensembl: ENSG00000172575 UniGene: Hs.591127 EntrezGene: 10125 Ensembl Chr15: 36567590 - 36644224 Strand: -1 GO terms: 0005085 0005088 0005509 0005515 0005622 0005624 0007242 0007264 0007265 0008270 0008289 0051056

Design shRNA
Chemistry RNA
Sequence (63b) GATCCCACACGTCCAGAGGATGGTGTTCAAGAGACACCATCCTCTGGACGTGTTTTTTGGAAA
Application gene silencing
Name RasGRP1-RNAi1419 , RasGRP1RNAi1419

References

A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells.Roose JP, Mollenauer M, Gupta VA, Stone J, Weiss A.Mol Cell Biol. 2005 Jun;25(11) :4426-41. Intrathecal Injections in Children With Spinal Muscular Atrophy: Nusinersen Clinical Trial Experience. Hache M, Swoboda KJ, Sethna N, Farrow-Gillespie A, Khandji A, Xia S, Bishop KM. J Child Neurol. 2016 Jun;31(7):899-906. PubMed:26823478

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