Sequence 1196(siTOP1.1)

Sequence siTOP1.1
Target	TOP1 (Homo sapiens)
Description	Topoisomerase (DNA) I Ensembl: ENSG00000103150
Design	siRNA
Chemistry	RNA
Sequence	siRNA sense (21b) GGATGATGCTGATTATAAATT / siRNA antisense (21b) TTTATAATCAGCATCATCCTC
Application	gene silencing
Name	siTOP1.1

References

Multiplexing siRNAs to compress RNAi-based screen size in human cells. Martin SE, Jones TL, Thomas CL, Lorenzi PL, Nguyen DA, Runfola T, Gunsior M, Weinstein JN, Goldsmith PK, Lader E, Huppi K, Caplen NJ. Nucleic Acids Res. 2007;35(8):e57.

Intrathecal Injections in Children With Spinal Muscular Atrophy: Nusinersen Clinical Trial Experience. Hache M, Swoboda KJ, Sethna N, Farrow-Gillespie A, Khandji A, Xia S, Bishop KM. J Child Neurol. 2016 Jun;31(7):899-906. PubMed:26823478

Background