Sequence 1198(LacZ)

Sequence LacZ
Target	TP53 ( Homo sapiens )
Description	Tumor protein p53 ( Li-Fraumeni syndrome ) Ensembl: ENSG00000141510 UniGene: Hs.654481 EntrezGene: 7157 Ensembl Chr17: 7512445 - 7531642 Strand: -1 GO terms: 0000060 0000739 0001701 0001836 0003677 0003700 0004518 0005507 0005515 0005524 0005626 0005634 0005654 0005657 0005730 0005737 0005739 0005783 0005829 0006284 0006289 0006350 0006355
Design	siRNA
Chemistry	RNA
Sequence	siRNA sense (20b) GCCAATATTGAAACCCACGG / siRNA antisense (20b) GTGGGTTTCAATATTGGCTT
Application	gene silencing
Name	LacZ

References

Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells.Scacheri PC, Rozenblatt-Rosen O, Caplen NJ, Wolfsberg TG, Umayam L, Lee JC, Hughes CM, Shanmugam KS, Bhattacharjee A, Meyerson M, Collins FS.Proc Natl Acad Sci U S A. 2004 Feb 17;101(7) :1892-7. Epub 2004 Feb 9.

Intrathecal Injections in Children With Spinal Muscular Atrophy: Nusinersen Clinical Trial Experience. Hache M, Swoboda KJ, Sethna N, Farrow-Gillespie A, Khandji A, Xia S, Bishop KM. J Child Neurol. 2016 Jun;31(7):899-906. PubMed:26823478

Background