Sequence 314 (Cul4A)

Sequence Cul4A
Target	CAND1 ( Homo sapiens )
Description	Cullin-associated and neddylation-dissociated 1 Ensembl: ENSG00000111530 UniGene: Hs.546407 EntrezGene: 55832 Ensembl Chr12: 65949426 - 65994658 Strand: 1 GO terms: 0000151 0005515 0005634 0006350 0006355 0016563 0016567 0030154 0043086 0045899
Design	siRNA
Chemistry	RNA
Sequence	siRNA sense (21b) GAACTTCCGAGACAGACCTTT / siRNA antisense (21b) AGGTCTGTCTCGGAAGTTCTT
Application	gene silencing
Name	Cul4A

References

Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage.Hu J, McCall CM, Ohta T, Xiong Y.Nat Cell Biol. 2004 Oct;6(10) :1003-9. Epub 2004 Sep 26.

Intrathecal Injections in Children With Spinal Muscular Atrophy: Nusinersen Clinical Trial Experience. Hache M, Swoboda KJ, Sethna N, Farrow-Gillespie A, Khandji A, Xia S, Bishop KM. J Child Neurol. 2016 Jun;31(7):899-906. PubMed:26823478

Background