Sequence 450 (Ddb2)

Sequence Ddb2
Target	DDB2 ( Homo sapiens )
Description	Damage-specific DNA binding protein 2, 48kDa Ensembl: ENSG00000012124
Design	siRNA
Chemistry	RNA
Sequence	siRNA sense (21b) GAGCGAGATCCGAGTTTACTT / siRNA antisense (21b) GTAAACTCGGATCTCGCTCTT
Application	gene silencing
Name	Ddb2

References

Targeted ubiquitination of CDT1 by the DDB1-CUL4A-ROC1 ligase in response to DNA damage.Hu J, McCall CM, Ohta T, Xiong Y.Nat Cell Biol. 2004 Oct;6(10) :1003-9. Epub 2004 Sep 26.

Intrathecal Injections in Children With Spinal Muscular Atrophy: Nusinersen Clinical Trial Experience. Hache M, Swoboda KJ, Sethna N, Farrow-Gillespie A, Khandji A, Xia S, Bishop KM. J Child Neurol. 2016 Jun;31(7):899-906. PubMed:26823478

Background