Sequence 488 (si 057)

Sequence si_057
Target	ERCC1 ( Homo sapiens )
Description	Excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) Ensembl: ENSG00000012061
Design	siRNA
Chemistry	RNA
Sequence	siRNA sense (21b) CGGACAGUCAGACCCUCCUGA / siRNA antisense (21b) AGGAGGGUCUGACUGUCCGUU
Application	gene silencing
Name	si_057

References

DSIR: assessing the design of highly potent siRNA by testing a set of cancer-relevant target genes. Filhol O, Ciais D, Lajaunie C, Charbonnier P, Foveau N, Vert JP, Vandenbrouck Y. PLoS One. 2012;7(10):e48057.

Intrathecal Injections in Children With Spinal Muscular Atrophy: Nusinersen Clinical Trial Experience. Hache M, Swoboda KJ, Sethna N, Farrow-Gillespie A, Khandji A, Xia S, Bishop KM. J Child Neurol. 2016 Jun;31(7):899-906. PubMed:26823478

Background