Sequence 742 (ERK2 2)
Sequence ERK2_2 | |
---|---|
Target | MAPK1 ( Homo sapiens ) |
Description | Mitogen-activated protein kinase 1
Ensembl: ENSG00000100030 UniGene: Hs.431850 EntrezGene: 5594 Ensembl Chr22: 20443946 - 20551970 Strand: -1 GO terms: 0000165 0000166 0001784 0004672 0004674 0004707 0004713 0005515 0005524 0005634 0005737 0006468 0006917 0006935 0006974 0007049 0007165 0007268 0009887 0016740 0019858 0031663 0032496 |
Design | siRNA |
Chemistry | RNA |
Sequence | siRNA sense (19b) AAACAGATCTTTACAAGCT / siRNA antisense (19b) AGCTTGTAAAGATCTGTTT |
Application | gene silencing |
Name | ERK2_2 |
References
Mechanisms regulating the constitutive activation of the extracellular signal-regulated kinase (ERK)signaling pathway in ovarian cancer and the effect of ribonucleic acid interference for ERK1/2 on cancer cell proliferation.Steinmetz R, Wagoner HA, Zeng P, Hammond JR, Hannon TS, Meyers JL, Pescovitz OH.Mol Endocrinol. 2004 Oct;18(10) :2570-82. Epub 2004 Jul 8.
Intrathecal Injections in Children With Spinal Muscular Atrophy: Nusinersen Clinical Trial Experience. Hache M, Swoboda KJ, Sethna N, Farrow-Gillespie A, Khandji A, Xia S, Bishop KM. J Child Neurol. 2016 Jun;31(7):899-906. PubMed:26823478