Sequence 743 (ERK2 3)

Sequence ERK2_3
Target	MAPK1 ( Homo sapiens )
Description	Mitogen-activated protein kinase 1 Ensembl: ENSG00000100030 UniGene: Hs.431850 EntrezGene: 5594 Ensembl Chr22: 20443946 - 20551970 Strand: -1 GO terms: 0000165 0000166 0001784 0004672 0004674 0004707 0004713 0005515 0005524 0005634 0005737 0006468 0006917 0006935 0006974 0007049 0007165 0007268 0009887 0016740 0019858 0031663 0032496
Design	siRNA
Chemistry	RNA
Sequence	siRNA sense (19b) CAAGAGGATTGAAGTAGAA / siRNA antisense (19b) TTCTACTTCAATCCTCTTG
Application	gene silencing
Name	ERK2_3

References

Mechanisms regulating the constitutive activation of the extracellular signal-regulated kinase (ERK)signaling pathway in ovarian cancer and the effect of ribonucleic acid interference for ERK1/2 on cancer cell proliferation.Steinmetz R, Wagoner HA, Zeng P, Hammond JR, Hannon TS, Meyers JL, Pescovitz OH.Mol Endocrinol. 2004 Oct;18(10) :2570-82. Epub 2004 Jul 8.

Intrathecal Injections in Children With Spinal Muscular Atrophy: Nusinersen Clinical Trial Experience. Hache M, Swoboda KJ, Sethna N, Farrow-Gillespie A, Khandji A, Xia S, Bishop KM. J Child Neurol. 2016 Jun;31(7):899-906. PubMed:26823478

Background