Sequence 1144(SOD1i-1)

Sequence SOD1i-1
Target	Sod1 ( Rattus norvegicus )
Description	Superoxide dismutase 1, soluble ( amyotrophic lateral sclerosis 1 ( adult ) ) Ensembl: ENSG00000142168 UniGene: Hs.443914 EntrezGene: 6647 Ensembl Chr21: 31953806 - 31963115 Strand: 1 GO terms: 0000187 0000303 0001541 0001819 0001890 0001895 0002262 0004785 0005507 0005615 0005634 0005737 0005739 0005759 0005777 0005829 0005886 0006302 0006309 0006749 0006801 0006879 0006916
Design	siRNA
Chemistry	RNA
Sequence	siRNA sense (21b) TCCTCACTCTAAGAAACATTT / siRNA antisense (21b) ATGTTTCTTAGAGTGAGGATT
Application	gene silencing
Name	SOD1i-1

References

Highly efficient small interfering RNA delivery to primary mammalian neurons induces MicroRNA-like effects before mRNA degradation.Davidson TJ, Harel S, Arboleda VA, Prunell GF, Shelanski ML, Greene LA, Troy CM.J Neurosci. 2004 Nov 10;24(45) :10040-6. J Neurosci. 2005 Feb 2;25(5) :1311.

Intrathecal Injections in Children With Spinal Muscular Atrophy: Nusinersen Clinical Trial Experience. Hache M, Swoboda KJ, Sethna N, Farrow-Gillespie A, Khandji A, Xia S, Bishop KM. J Child Neurol. 2016 Jun;31(7):899-906. PubMed:26823478

Background